منابع مشابه
QTL mapping to QTL cloning: mice to the rescue.
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متن کاملR/qtl: high-throughput multiple QTL mapping
MOTIVATION R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of experimental cross types. We recently added multiple QTL mapping (MQM) to R/qtl. MQM adds higher statistical power to detect and disentangle the effects of multiple linked and unlinked QTL compared with many other metho...
متن کاملR/qtl: QTL Mapping in Experimental Crosses
SUMMARY R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by ...
متن کاملPrinciples of QTL Mapping
To date, most genetic progress for quantitative traits in livestock has been made by selection on phenotype or on estimates of breeding values (EBV) derived from phenotype, without knowledge of the number of genes that affect the trait or the effects of each gene. In this quantitative genetic approach to genetic improvement, the genetic architecture of traits of interest has essentially been tr...
متن کاملFrom QTL Mapping to eQTL Analysis
Genetic loci that affect mRNA expression levels of other genes are referred to as expression quantitative trait loci (eQTL). Discovering eQTLs by combining gene expression data with genetic marker data is an important means to understand gene regulation and to study disease mechanisms. EQTL mapping has been studied in many species, e.g., yeast [1, 2], eucalyptus [3], mice [4–6], rats [7], and h...
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ژورنال
عنوان ژورنال: Journal of Statistical Software
سال: 2010
ISSN: 1548-7660
DOI: 10.18637/jss.v032.b05